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Knowledge Centre / Bone Cancer (Primary)

Bone Cancer (Primary)

Overview of osteosarcoma, Ewing sarcoma, and chondrosarcoma.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
OncologyMusculoskeletalOrthopaedics

Clinical Guidelines

ESMO Clinical Practice Guideline: Bone Sarcomas
National
NICE CKS: Bone and soft tissue sarcoma - recognition and referral
National
Scottish referral guidelines for suspected cancer
National
ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up: Bone sarcomas
Local
NCCN Clinical Practice Guidelines in Oncology: Bone Cancer (Version 2.2023)
Local

Recent iatroX Q&As

  • What are the key clinical features that differentiate osteosarcoma, Ewing sarcoma, and chondrosarcoma in a young patient presenting with bone pain?Updated: 8/22/2025
  • Which imaging modalities are recommended for the initial assessment of suspected primary bone cancer in primary care?Updated: 8/22/2025
  • What are the referral criteria for a suspected case of primary bone cancer to a specialist service?Updated: 8/22/2025
  • How should I approach the management of pain in a patient diagnosed with osteosarcoma undergoing treatment?Updated: 8/22/2025
  • What are the common metastatic sites for primary bone cancers, and how should I monitor for these in follow-up care?Updated: 8/22/2025
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