What are the key indications for initiating parenteral nutrition in adult patients?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Parenteral nutrition should be considered in adult patients who are malnourished or at risk of malnutrition as defined in recommendations 1.3.1 and 1.3.2, and meet either of the following criteria: inadequate or unsafe oral and/or enteral nutritional intake or a non-functional, inaccessible or perforated (leaking) gastrointestinal tract .

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