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How should I manage a patient with laryngeal cancer who presents with pain and difficulty swallowing?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 22 August 2025

Management of a patient with laryngeal cancer presenting with pain and difficulty swallowing should include:

  • Assessment: Confirm diagnosis with biopsy and imaging (MRI or CT) to stage the tumour and plan treatment appropriately. Consider FDG PET-CT for systemic staging if advanced disease is suspected (beyond T2N0) 1.
  • Symptom management: Assess and support nutritional status early, including consideration of enteral nutrition or prophylactic feeding tube placement due to dysphagia 1.
  • Treatment options: For early-stage (T1-T2) laryngeal squamous cell carcinoma, offer transoral laser microsurgery or radiotherapy 1.
  • For advanced disease (T3), discuss with the patient the choice between radiotherapy with concomitant chemotherapy or surgery with adjuvant radiotherapy, considering swallowing function and airway status 1.
  • For T4a disease, surgery with adjuvant radiotherapy, with or without chemotherapy, is recommended 1.
  • Supportive care: Involve speech and language therapy for swallowing exercises and voice therapy as needed 1.
  • Palliative care: If airway obstruction or severe symptoms occur, consider endoluminal debulking rather than tracheostomy and involve palliative care teams 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.