What are the current guidelines for the management and treatment of Korsakoff Syndrome in primary care?

Management and treatment of Korsakoff syndrome in primary care involves primarily prevention and supportive care.

People at high risk of developing Wernicke-Korsakoff syndrome, such as those with alcohol dependence, malnourishment, or decompensated liver disease, should be offered parenteral thiamine followed by oral thiamine to prevent progression to Korsakoff syndrome. This is especially important during planned assisted alcohol withdrawal or hospital admission for acute illness or injury ¹,².

For patients with established Wernicke-Korsakoff syndrome, long-term care arrangements should be made according to the severity of cognitive impairment: supported independent living for mild impairment and supported 24-hour care for moderate to severe impairment. The care environment should be adapted to cognitive needs, and support should be provided to maintain abstinence from alcohol ¹.

Referral to specialist services is recommended for comprehensive assessment and management, including mental health support if comorbid psychiatric disorders are present ¹.