When should I consider referring a male patient for specialist fertility assessment?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Consider referring a male patient for specialist fertility assessment if:

  • He has been trying to conceive with his partner for 1 year or more without success, and there is no known cause of infertility.
  • There is a known clinical cause of infertility or a history of predisposing factors for infertility.
  • The male patient has chronic viral infections such as hepatitis B, hepatitis C, or HIV, requiring specialist expertise for safe risk-reduction investigation and treatment.
  • There is evidence of abnormal semen analysis results, such as azoospermia or severe oligozoospermia, especially if confirmed on repeat testing.
  • He has hypogonadotrophic hypogonadism, which may benefit from specialist medical management.
  • He has obstructive azoospermia, where surgical correction might be considered by specialists.
  • Early referral is warranted if fertility-threatening treatments (e.g., cancer treatment) are planned.

Referral should be made to a specialist fertility team to improve the effectiveness and efficiency of treatment and to provide appropriate counselling and support.

Educational content only. Always verify information and use clinical judgement.