What are the recommended first-line antiretroviral therapy (ART) regimens for newly diagnosed HIV patients?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Recommended first-line antiretroviral therapy (ART) regimens for patients newly diagnosed with HIV are not explicitly detailed in the provided UK guideline excerpts.

The supplied context focuses primarily on HIV testing strategies and hepatitis B management, without specifying first-line ART regimens for newly diagnosed HIV patients.

For current UK clinical practice, first-line ART typically involves a combination of two nucleoside reverse transcriptase inhibitors (NRTIs) plus a third agent, such as an integrase strand transfer inhibitor (INSTI), but this specific guidance is not included in the provided excerpts.

It is recommended to consult the latest British HIV Association (BHIVA) guidelines or NHS England commissioning policies for detailed first-line ART regimen recommendations.

Educational content only. Always verify information and use clinical judgement.