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How effective are proton pump inhibitors (PPIs) in managing symptoms associated with hiatal hernias, and are there any specific guidelines for their u
Answer
Effectiveness of Proton Pump Inhibitors (PPIs) in Hiatal Hernia Symptom Management
PPIs are effective in managing symptoms associated with hiatal hernias primarily by suppressing acid reflux, which is a common symptom in these patients. They are recommended as first-line therapy for gastro-oesophageal reflux disease (GORD), which often coexists with hiatal hernias, to reduce acid-related symptoms such as heartburn and regurgitation.
Guidelines for Use
- Offer a full-dose PPI for 4 to 8 weeks to people with GORD symptoms, which includes those with hiatal hernias causing reflux symptoms.
- If symptoms recur after initial treatment, step down to the lowest effective dose to control symptoms and discuss on-demand use to manage symptoms independently.
- Consider referral to a specialist if symptoms are non-responsive to PPI therapy or if there are alarm features.
- Long-term PPI therapy may be considered in cases such as oesophageal stricture dilation, but generally, annual review and attempts to step down or stop treatment are advised.
PPIs do not treat the anatomical defect of the hiatal hernia but effectively control acid reflux symptoms associated with it. Surgical options like laparoscopic fundoplication may be considered for patients with confirmed acid reflux who respond to PPIs but prefer not to continue long-term medication or cannot tolerate PPIs.
Therefore, PPIs are effective for symptom control in hiatal hernia-related reflux but should be used according to symptom response and reviewed regularly to minimize long-term use.
References: 1
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