What criteria should I use to determine whether a patient with epiglottitis requires urgent referral to secondary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Criteria for urgent referral of a patient with epiglottitis to secondary care include:

  • Signs of respiratory distress such as severe respiratory difficulty, stridor, or inability to maintain oxygen saturation despite oxygen supplementation.
  • Evidence of airway compromise or risk of sudden airway obstruction, including drooling, difficulty swallowing, or muffled voice.
  • Any features suggesting an immediately life-threatening illness, such as altered mental state, cyanosis, or shock.
  • Presence of high-risk features for severe illness or sepsis, including raised respiratory rate, low blood pressure, mottled or cyanotic skin, or non-blanching rash.
  • Clinical judgement indicating the patient is seriously unwell or deteriorating rapidly.

Patients meeting any of these criteria should be referred immediately for emergency medical care, usually by ambulance, to a facility with appropriate resuscitation and airway management capabilities ,.

Educational content only. Always verify information and use clinical judgement.