Initial investigations for a patient presenting with symptoms suggestive of Conversion Disorder should primarily focus on excluding other neurological and medical conditions that could explain the symptoms. This typically includes a thorough clinical assessment and targeted investigations such as blood tests (full blood count, urea and electrolytes, liver function, thyroid function, inflammatory markers like erythrocyte sedimentation rate or C-reactive protein), urinalysis, and possibly imaging or specialist referral if new neurological signs are present or if the diagnosis is uncertain. Routine neurological imaging is not indicated unless there are specific clinical features suggesting an organic cause. If the patient has a known functional neurological disorder and no new signs, re-referral or extensive investigations may not be necessary. Clinical judgement is essential to decide on additional tests to exclude other diagnoses, and referral to a specialist should be considered if uncertainty remains or new symptoms develop.
What initial investigations should be considered for a patient presenting with symptoms suggestive of Conversion Disorder?
Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.
Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX