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What investigations are recommended to confirm the diagnosis of Charcot foot in diabetic patients?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 22 August 2025

Recommended investigations to confirm the diagnosis of Charcot foot in diabetic patients include:

  • Arrange a weight-bearing X-ray of the affected foot and ankle to identify characteristic changes associated with acute Charcot arthropathy.
  • If the X-ray is normal but clinical suspicion remains high, consider an MRI to detect early bone and soft tissue changes not visible on X-ray.
  • Refer the patient urgently (within 1 working day) to a multidisciplinary foot care service for further assessment and management.
  • Use clinical assessment including monitoring foot-skin temperature differences and serial X-rays to support diagnosis and monitor progression.

These steps help differentiate Charcot arthropathy from other causes of foot redness, swelling, and deformity in diabetic patients, especially in the presence of peripheral neuropathy or renal failure.

References: 1

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This content was generated by iatroX. Always verify information and use clinical judgment.