Which diagnostic tests are recommended for confirming the presence of valvular heart disease in primary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Recommended diagnostic test in primary care for confirming valvular heart disease is echocardiography. Consider an echocardiogram for adults with a murmur and no other signs or symptoms if valve disease is suspected based on the nature of the murmur, family history, age (especially if over 75), or medical history such as atrial fibrillation. Offer an echocardiogram to adults with a murmur if valve disease is suspected and they have signs (e.g., peripheral oedema), symptoms (e.g., angina or breathlessness), or an abnormal ECG, or an ejection systolic murmur with a reduced second heart sound but no other signs or symptoms. If valve disease is suspected with a systolic murmur and exertional syncope, or severe symptoms thought related to valve disease, urgent echocardiography (within 2 weeks) is recommended. Other tests such as ECG may support suspicion but echocardiography is the key diagnostic tool to confirm valvular heart disease in primary care before specialist referral.

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