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Which diagnostic tests are recommended for confirming a suspected case of typhus in a patient with recent travel history?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 22 August 2025

Diagnostic tests for confirming suspected typhus in a patient with recent travel history:

The provided UK guidelines do not specifically address diagnostic tests for typhus. However, typhus diagnosis generally relies on serological testing to detect antibodies against Rickettsia species, the causative agents of typhus. Commonly used tests include indirect immunofluorescence assay (IFA) and enzyme-linked immunosorbent assay (ELISA) for IgM and IgG antibodies. Polymerase chain reaction (PCR) testing on blood or tissue samples can also be used for early detection.

Given the absence of direct UK guideline recommendations for typhus in the provided context, it is advisable to refer to infectious disease specialists or national reference laboratories for appropriate testing. Clinical suspicion based on travel history and symptoms should guide testing decisions.

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This content was generated by iatroX. Always verify information and use clinical judgment.