What are the current guidelines for antibiotic treatment in confirmed cases of Group A Streptococcal pharyngitis?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

The provided UK guideline excerpts do not contain specific recommendations for antibiotic treatment in confirmed cases of Group A Streptococcal pharyngitis ,,.

However, general principles for managing acute respiratory infections (ARIs), which include sore throat, are outlined . For individuals with symptoms of an ARI, a clinical assessment should be used to make a diagnosis and decide whether to prescribe antimicrobials, either immediately or as a back-up prescription . Self-care advice should also be offered . When making prescribing decisions, a person's overall health and social circumstances should be considered, with a potentially lower threshold for treatment or referral for those at higher risk of poor outcomes, such as individuals with comorbidities or frailty .

Antimicrobial stewardship guidelines emphasise the importance of local system-wide approaches to reduce inappropriate antimicrobial demand and use . Resources should be available for healthcare professionals to inform the public about self-limiting infections, encouraging self-management when safe . This includes advice on recognising self-limiting infections, seeking further advice if unsure, managing symptoms at home, and identifying red flag symptoms that warrant medical help .

Educational content only. Always verify information and use clinical judgement.