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What are the key clinical features that suggest a diagnosis of metastatic spinal cord compression (MSCC) in a patient?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 22 August 2025
When considering a diagnosis of metastatic spinal cord compression (MSCC), particularly in patients with a past, current, or suspected diagnosis of cancer, several key clinical features should prompt suspicion 1. These symptoms and signs directly suggest cord compression:
- Bladder or bowel dysfunction 1.
- Gait disturbance or difficulty walking 1.
- Limb weakness 1.
- Neurological signs of spinal cord or cauda equina compression 1.
- Numbness, paraesthesia, or sensory loss 1.
- Radicular pain 1.
If a patient with a past or current diagnosis of cancer presents with these symptoms or signs of cord compression, it should be treated as an oncological emergency, and the MSCC coordinator should be contacted immediately 1.
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