What are the indications for antibiotic therapy in patients with cutaneous abscesses?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

The provided UK guidelines do not specifically detail the indications for antibiotic therapy in patients with general cutaneous abscesses.

However, the guidelines do provide information on antibiotic use for specific types of infections and abscesses:

  • Diabetic Foot Infections: Antibiotics are indicated for moderate or severe diabetic foot infections, with choices guided by microbiological results when available . Specific antibiotics are also recommended if MRSA or Pseudomonas aeruginosa infection is suspected or confirmed in diabetic foot problems .
  • Diverticular Abscesses: Intravenous antibiotics are offered to people with acute diverticulitis and suspected diverticular abscesses, particularly in secondary care settings . The choice of antibiotic for diverticular abscesses should follow specific recommendations, and intravenous antibiotics should be reviewed within 48 hours or after scanning, with consideration for stepping down to oral antibiotics .

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