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When should I consider referring a patient experiencing severe side effects from chemotherapy to a specialist?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 21 August 2025

You should consider referring a patient experiencing severe side effects from chemotherapy to a specialist immediately, particularly if neutropenic sepsis is suspected 2. Neutropenic sepsis should be suspected in patients undergoing anticancer treatment who become unwell 2. Patients with suspected neutropenic sepsis require immediate referral for assessment in secondary or tertiary care 2. This condition must be treated as an acute medical emergency 2. Patients and their carers are typically provided with information on how and when to contact 24-hour specialist oncology advice and how and when to seek emergency care for chemotherapy-related complications 2. For patients receiving high-intensity chemotherapy, especially those in ambulatory care, there should be clear pathways for rapid hospital assessment in the event of neutropenic sepsis or other chemotherapy-related complications or toxicities 1. Haematology units caring for patients receiving high-intensity chemotherapy should ensure consultant-level specialist medical staff are available 24 hours a day 1.

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