What are the indications for referring a patient with thyroiditis to an endocrinologist?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 17 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Indications for referring a patient with thyroiditis to an endocrinologist include:

  • Suspected subacute thyroiditis .
  • The presence of a goitre, nodule, or structural change in the thyroid gland . If malignancy is suspected, referral should be made via a suspected cancer pathway ,,.
  • Atypical or difficult to interpret thyroid function tests (TFTs) .
  • Suspected associated endocrine disease, such as Addison's disease . It is crucial not to start thyroid hormone replacement before specialist glucocorticoid replacement in suspected adrenal failure, as this can precipitate an adrenal crisis .
  • If the patient is a female planning a pregnancy .
  • A persistently raised thyroid-stimulating hormone (TSH) despite adequate or escalating levothyroxine (LT4) treatment doses .
  • For adults with subclinical hyperthyroidism, consider seeking specialist advice if they have two TSH readings lower than 0.1 mIU/litre at least three months apart, and evidence of thyroid disease (for example, a goitre or positive thyroid antibodies) or symptoms of thyrotoxicosis .
  • For all children and young people with subclinical hyperthyroidism, specialist advice should be considered .

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