What are the potential complications of a peritonsillar abscess that I should be aware of during management?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 17 August 2025Updated: 17 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

During the management of a peritonsillar abscess, it is important for an Admin in General Practice to be aware of several potential complications . A significant concern is the risk of airway obstruction, which can be life-threatening [1, ]. The infection may also spread beyond the tonsillar capsule into adjacent deep neck spaces . This spread can lead to more severe conditions such as a parapharyngeal abscess or even mediastinitis, which is an infection of the chest cavity . Another serious, though less common, complication is internal jugular vein thrombosis, also known as Lemierre's syndrome, which can result from the spread of infection . There is also a risk of aspiration of pus, particularly if the abscess ruptures spontaneously . Furthermore, even after successful initial management, there is a possibility of recurrence of the peritonsillar abscess [1, ].

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