What criteria should I use to determine if a patient with Peyronie's disease requires referral to a specialist?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 17 August 2025Updated: 17 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

A patient with Peyronie's disease, which is a penile structural abnormality, should be referred to a urology specialist .

Additionally, if there is a penile mass or a persistent penile lesion, an urgent referral using a two-week pathway should be arranged to exclude penile intraepithelial neoplasia or malignancy ,,. This urgent referral is also considered for unexplained or persistent symptoms affecting the foreskin or glans ,.

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