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How often should patients with a history of variceal bleeding be monitored for recurrence of varices?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 17 August 2025

UK clinical guidelines primarily focus on the initial detection of oesophageal varices in patients with cirrhosis and the primary prevention of bleeding, rather than specifying a routine monitoring frequency for the recurrence of varices after a bleeding event and subsequent treatment 2,3. For individuals with cirrhosis, an upper gastrointestinal endoscopy is offered to detect oesophageal varices unless they are planning to take carvedilol or propranolol for primary prevention of decompensation 2. If no varices are found during an initial endoscopy and the patient is not taking carvedilol or propranolol, surveillance endoscopy is offered every 3 years 2,3. If medium or large varices are detected, treatment options for primary prevention of bleeding include carvedilol or propranolol, or endoscopic variceal band ligation 2. For acute variceal bleeding, band ligation is used 1.

Regarding monitoring for recurrence after variceal eradication, such as by band ligation, a prospective randomized trial investigated endoscopic follow-up intervals. This study compared endoscopic follow-up at 3 months versus 6 months after oesophageal variceal eradication by band ligation in patients with cirrhosis ((Debernardi Venon et al., 2014)).

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