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How should I approach the management of a patient with Duchenne muscular dystrophy regarding corticosteroid therapy?
Answer
The management of a patient with Duchenne muscular dystrophy regarding corticosteroid therapy has historically included the use of corticosteroids [ (Moxley RT 3rd et al., 2005) ]. While specific current UK guidelines on corticosteroid therapy for Duchenne muscular dystrophy are not provided in the context, general principles for managing patients on oral corticosteroids are relevant 4. When a patient is prescribed long-term oral corticosteroids, it is important to be aware of potential side effects and the need for careful management 4. These can include a range of adverse effects, and the patient's care plan should address these 4. Furthermore, long-term corticosteroid use can lead to adrenal insufficiency, which requires careful identification and management 7. Patients on long-term corticosteroids should not stop treatment abruptly without medical advice due to the risk of adrenal crisis 4,7. Regular monitoring and a clear management plan are essential for patients receiving corticosteroid therapy 4.
Key References
- CKS - Cushing's syndrome
- NG119 - Cerebral palsy in adults
- CKS - Croup
- CKS - Corticosteroids - oral
- NG42 - Motor neurone disease: assessment and management
- NG115 - Chronic obstructive pulmonary disease in over 16s: diagnosis and management
- NG243 - Adrenal insufficiency: identification and management
- (Moxley RT 3rd et al., 2005): Practice parameter: corticosteroid treatment of Duchenne dystrophy [RETIRED]: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society.
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