How should I approach the management of a patient with Duchenne muscular dystrophy regarding corticosteroid therapy?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 17 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

The management of a patient with Duchenne muscular dystrophy regarding corticosteroid therapy has historically included the use of corticosteroids [ ]. While specific current UK guidelines on corticosteroid therapy for Duchenne muscular dystrophy are not provided in the context, general principles for managing patients on oral corticosteroids are relevant . When a patient is prescribed long-term oral corticosteroids, it is important to be aware of potential side effects and the need for careful management . These can include a range of adverse effects, and the patient's care plan should address these . Furthermore, long-term corticosteroid use can lead to adrenal insufficiency, which requires careful identification and management . Patients on long-term corticosteroids should not stop treatment abruptly without medical advice due to the risk of adrenal crisis ,. Regular monitoring and a clear management plan are essential for patients receiving corticosteroid therapy .

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