What investigations are recommended to confirm a diagnosis of Mallory-Weiss tear in primary care settings?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 17 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Investigations to confirm a diagnosis of Mallory-Weiss tear are generally not performed in primary care settings . Mallory-Weiss tears are a cause of acute upper gastrointestinal bleeding, which necessitates urgent assessment and management in a hospital environment .

The definitive investigation for confirming a Mallory-Weiss tear is upper gastrointestinal endoscopy . This procedure allows for direct visualisation of the tear and, if active bleeding is present, enables therapeutic interventions such as endoscopic hemoclip placement or epinephrine injection .

In primary care, the focus is on recognising the signs and symptoms of acute upper gastrointestinal bleeding and arranging urgent referral to secondary care for definitive diagnosis and management .

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