When should I consider referring a patient with suspected Adult-Onset Still's Disease to a rheumatologist?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 17 August 2025Updated: 17 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Consider referring a patient with suspected adult-onset Still's disease to a rheumatologist urgently if they present with persistent inflammatory arthritis or synovitis of unknown cause, especially if multiple joints are involved or symptoms have persisted for 3 months or more. Do not delay referral based on normal blood tests or pending results. Early specialist assessment is important to confirm diagnosis and initiate appropriate management. In primary care, avoid prescribing glucocorticoids before specialist review as they may mask key clinical features and delay diagnosis.

Adult-onset Still's disease is a systemic inflammatory condition often presenting with fever, rash, and arthritis; persistent synovitis or inflammatory arthritis should prompt referral to rheumatology for specialist assessment.

Educational content only. Always verify information and use clinical judgement.