
AI-powered clinical assistant for UK healthcare professionals
What are the key clinical signs and symptoms to recognize compartment syndrome in a patient presenting with limb pain?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 17 August 2025
Key clinical signs and symptoms to recognize compartment syndrome in a patient presenting with limb pain include:
- Severe pain disproportionate to the injury that is persistent and worsens despite analgesia, often described as deep and burning in nature 1 (Frink et al., 2010).
- Pain on passive stretch of the muscles within the affected compartment, which is an early and sensitive clinical indicator 1 (Frink et al., 2010).
- Tense, swollen compartment on palpation, indicating increased intracompartmental pressure 1 (Frink et al., 2010).
- Paresthesia or sensory deficits in the distribution of nerves passing through the compartment, reflecting early nerve ischemia 1 (Frink et al., 2010).
- Muscle weakness or paralysis may develop as the syndrome progresses, indicating muscle and nerve compromise 1 (Frink et al., 2010).
- Pallor and pulselessness are late signs and may indicate vascular compromise; however, pulses can be present early in compartment syndrome and their absence is not required for diagnosis 1 (Frink et al., 2010).
Early recognition relies heavily on clinical assessment focusing on pain characteristics and neurological symptoms, as compartment pressure measurement is not always immediately available or definitive 1 (Frink et al., 2010). Prompt diagnosis and surgical intervention are critical to prevent permanent tissue damage.
Key References
- NG37 - Fractures (complex): assessment and management
- CKS - Peripheral arterial disease
- CKS - Leg ulcer - venous
- NG211 - Rehabilitation after traumatic injury
- CKS - Sprains and strains
- CG147 - Peripheral arterial disease: diagnosis and management
- (Frink et al., 2010): Compartment syndrome of the lower leg and foot.
Related Questions
Finding similar questions...