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What are the current first-line treatment options for managing mild to moderate ulcerative colitis in adults?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025
For adults with mild to moderate ulcerative colitis, the current first-line treatment options include a topical aminosalicylate as the initial therapy. 1
If remission is not achieved within 4 weeks, consider adding an oral aminosalicylate. 1
In cases where further treatment is needed, a time-limited course of corticosteroids may be considered. 1
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