For a patient presenting with unexplained weight loss and abdominal pain, consider referring using a suspected cancer pathway referral for oesophageal or stomach cancer if they are aged 55 and over with upper abdominal pain and weight loss NICE NG12.
If the patient is aged 55 and over with weight loss and low haemoglobin levels, raised platelet count, nausea, or vomiting, consider a non-urgent, direct access upper gastrointestinal endoscopy NICE NG12.
If the patient is aged 40 and over with unexplained abdominal pain and weight loss, offer quantitative faecal immunochemical testing to investigate colorectal cancer NICE NG12.
In cases where there is suspicion of pancreatic cancer with weight loss and abdominal pain in patients aged 60 and over, consider an urgent, direct access CT scan (to be done within 2 weeks) or an urgent ultrasound scan if CT is unavailable NICE NG12.