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What are the recommended first-line treatment options for newly diagnosed multiple myeloma in adults?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025
The recommended first-line treatment options for adults with newly diagnosed multiple myeloma include bortezomib in combination with dexamethasone, or with dexamethasone and thalidomide, for those eligible for high-dose chemotherapy with stem cell transplantation 1.
For patients in whom high-dose chemotherapy is considered inappropriate, thalidomide in combination with an alkylating agent and a corticosteroid is recommended as an option 1.
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