Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX
Management of a child diagnosed with rickets due to vitamin D deficiency involves:
- Referral: Arrange referral to a paediatrician for children with clinical features of rickets before starting treatment NICE CKS.
- Vitamin D supplementation: Initiate high-dose vitamin D treatment for 8–12 weeks to rapidly correct deficiency, typically using cholecalciferol (vitamin D3) as per Royal Osteoporosis Society (ROS) guidelines NICE CKS.
- Dosage: Although exact dosing should be guided by specialist advice, high-dose regimens often involve daily doses of 2000 IU to 6000 IU vitamin D3 for 8–12 weeks, followed by maintenance doses NICE CKS. The British National Formulary for Children supports reducing to maintenance doses after 8–12 weeks to avoid hypercalcaemia NICE CKS.
- Maintenance therapy: After loading, maintain vitamin D supplementation at 400–600 IU daily to sustain adequate levels and prevent recurrence NICE CKS.
- Calcium intake: Assess dietary calcium intake and advise increasing calcium-rich foods; if inadequate, consider calcium supplementation as many children with vitamin D deficiency are also calcium deficient NICE CKS. Recommended daily calcium intake to prevent rickets is 200 mg (birth to 6 months), 260 mg (6–12 months), and >500 mg (over 12 months) NICE CKS.
- Monitoring and follow-up: Arrange follow-up to reassess serum 25(OH)D and bone profile levels and monitor symptoms NICE CKS. Routine monitoring is not required if the child is asymptomatic and compliant with therapy NICE CKS.
- Lifestyle advice: Advise on safe sunlight exposure and dietary sources of vitamin D to maintain adequate levels NICE CKS.