In women aged under 40 years who have not conceived after 2 years of regular unprotected intercourse or 12 cycles of artificial insemination, offer 3 full cycles of IVF, with or without ICSI. NICE CG156
In women aged 40 to 42 years who have not conceived after 2 years of regular unprotected intercourse or 12 cycles of artificial insemination, offer 1 full cycle of IVF, with or without ICSI, provided they have never previously had IVF, there is no evidence of low ovarian reserve, and there has been a discussion of the additional implications of IVF and pregnancy at this age. NICE CG156
For couples where investigations show no chance of pregnancy with expectant management and IVF is the only effective treatment, refer the woman directly to a specialist team for IVF treatment. NICE CG156
Discuss the risks and benefits of IVF in accordance with the current HFEA Code of Practice when considering IVF as a treatment option. NICE CG156
Offer investigations earlier than 1 year for couples identified as less likely to conceive, based on clinical judgment. NICE CG156