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What are the recommended screening protocols for gestational diabetes in pregnant women?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

Recommended screening protocols for gestational diabetes mellitus (GDM) in pregnant women:

  • At the booking appointment, assess risk factors for GDM including BMI above 30 kg/m2, previous macrosomic baby weighing 4.5 kg or more, previous gestational diabetes, family history of diabetes (first-degree relative), and ethnicity with a high prevalence of diabetes. Women with any of these risk factors should be offered testing for GDM 1.
  • Do not use fasting plasma glucose, random blood glucose, HbA1c, glucose challenge test, or urinalysis for glucose to assess risk of developing GDM 1.
  • For women with previous gestational diabetes, offer early self-monitoring of blood glucose or a 75-g 2-hour oral glucose tolerance test (OGTT) as soon as possible after booking (first or second trimester), and a further 75-g 2-hour OGTT at 24 to 28 weeks if the first OGTT is normal 1.
  • For women with other risk factors, offer a 75-g 2-hour OGTT at 24 to 28 weeks gestation 1.
  • Consider further testing to exclude GDM in women with glycosuria of 2+ or above on one occasion or glycosuria of 1+ or above on two or more occasions during routine antenatal care 1.
  • Diagnose GDM if fasting plasma glucose is 5.6 mmol/l or above, or 2-hour plasma glucose is 7.8 mmol/l or above following the OGTT 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.