What are the key clinical features to consider when assessing a patient for obstructive sleep apnea (OSA)?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

When assessing a patient for obstructive sleep apnoea/hypopnoea syndrome (OSAHS) in individuals over 16 years, key clinical features from a sleep history and the presence of certain associated conditions should be considered .

  • Key Clinical Features from Sleep History

Suspect OSAHS if a patient presents with two or more of the following features from their sleep history :

  • Snoring
  • Witnessed apnoeas
  • Unrefreshing sleep
  • Waking headaches
  • Unexplained excessive sleepiness, tiredness, or fatigue
  • Nocturia (waking from sleep to urinate)
  • Choking during sleep
  • Sleep fragmentation or insomnia
  • Cognitive dysfunction or memory impairment
  • Conditions with Higher Prevalence of OSAHS

Be aware that OSAHS has a higher prevalence in people with any of the following conditions :

  • Obesity or overweight (including in pregnancy)
  • Treatment-resistant hypertension
  • Type 2 diabetes
  • Cardiac arrhythmia, particularly atrial fibrillation
  • Stroke or transient ischaemic attack
  • Chronic heart failure
  • Moderate or severe asthma
  • Polycystic ovary syndrome
  • Down's syndrome
  • Non-arteritic anterior ischaemic optic neuropathy (sudden loss of vision in one eye due to decreased blood flow to the optic nerve)
  • Hypothyroidism
  • Acromegaly
  • Assessment Scales

For preliminary assessment of sleepiness, the Epworth Sleepiness Scale should be used . Additionally, consider using the STOP-Bang Questionnaire . It is important not to rely solely on the Epworth Sleepiness Scale to determine the need for referral, as not all individuals with OSAHS experience excessive sleepiness .

Educational content only. Always verify information and use clinical judgement.