Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX
The most effective management options for acne vulgaris, as first-line treatments, are determined by the severity of the acne NICE NG198. A 12-week course of treatment is typically offered NICE NG198.
- For any acne severity:
- A fixed combination of topical adapalene with topical benzoyl peroxide, applied once daily in the evening NICE NG198.
- A fixed combination of topical tretinoin with topical clindamycin, applied once daily in the evening NICE NG198.
- For mild to moderate acne:
- A fixed combination of topical benzoyl peroxide with topical clindamycin, applied once daily in the evening NICE NG198.
- For moderate to severe acne:
- A fixed combination of topical adapalene with topical benzoyl peroxide, applied once daily in the evening, combined with either oral lymecycline or oral doxycycline taken once daily NICE NG198.
- Topical azelaic acid combined with either oral lymecycline or oral doxycycline NICE NG198.
Maintenance Treatment:
Maintenance treatment may be considered for individuals with a history of frequent relapse after initial treatment NICE NG198. A fixed combination of topical adapalene and topical benzoyl peroxide is a recommended option for maintenance NICE NG198. If this is not tolerated or if one component is contraindicated, topical monotherapy with adapalene, azelaic acid, or benzoyl peroxide can be considered NICE NG198. Maintenance treatments should be reviewed after 12 weeks to determine if they should continue NICE NG198.