Acne

The most effective management options for acne vulgaris, as first-line treatments, are determined by the severity of the acne ¹. A 12-week course of treatment is typically offered ¹.

• For any acne severity:
  • A fixed combination of topical adapalene with topical benzoyl peroxide, applied once daily in the evening ¹.
  • A fixed combination of topical tretinoin with topical clindamycin, applied once daily in the evening ¹.
• For mild to moderate acne:
  • A fixed combination of topical benzoyl peroxide with topical clindamycin, applied once daily in the evening ¹.
• For moderate to severe acne:
  • A fixed combination of topical adapalene with topical benzoyl peroxide, applied once daily in the evening, combined with either oral lymecycline or oral doxycycline taken once daily ¹.
  • Topical azelaic acid combined with either oral lymecycline or oral doxycycline ¹.

Maintenance Treatment:

Maintenance treatment may be considered for individuals with a history of frequent relapse after initial treatment ¹. A fixed combination of topical adapalene and topical benzoyl peroxide is a recommended option for maintenance ¹. If this is not tolerated or if one component is contraindicated, topical monotherapy with adapalene, azelaic acid, or benzoyl peroxide can be considered ¹. Maintenance treatments should be reviewed after 12 weeks to determine if they should continue ¹.