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What are the recommended first-line topical treatments for a child diagnosed with impetigo?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025
Recommended first-line topical treatments for a child diagnosed with impetigo:
- For localized non-bullous impetigo in children who are not systemically unwell or at high risk of complications, hydrogen peroxide 1% cream applied two to three times daily for 5 days is recommended as the first-line treatment.
- If hydrogen peroxide 1% cream is unsuitable (for example, if the impetigo is around the eyes), topical fusidic acid 2% cream applied three times daily for 5 days should be offered.
- If fusidic acid resistance is suspected or confirmed, topical mupirocin 2% cream applied three times daily for 5 days is recommended as an alternative.
Reassessment is advised if symptoms worsen rapidly or do not improve after completing the treatment course.
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