When should I refer a patient for specialist assessment regarding HRT management?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Refer a patient for specialist assessment regarding hormone replacement therapy (HRT) management if they have ongoing symptoms and lifestyle measures, hormonal, non-hormonal, or non-drug treatments are ineffective .

Refer if the patient has persistent, troublesome adverse effects from treatment .

Refer if there is uncertainty about the most suitable treatment option, for example if the woman has co-morbidities and/or contraindications to treatment .

Refer if there is a sudden change in menstrual pattern, intermenstrual bleeding, postcoital bleeding, or postmenopausal bleeding, to assess appropriately and arrange an urgent 2-week referral if a gynaecological cancer is suspected .

Refer women with premature ovarian insufficiency or if there is doubt about the diagnosis, to a specialist with expertise in menopause or reproductive medicine .

Refer women with menopause-associated symptoms and a personal history, or high risk, of breast cancer for specialist advice .

Refer women with menopause due to medical or surgical treatment to discuss menopause and fertility with a healthcare professional with expertise in menopause .

Educational content only. Always verify information and use clinical judgement.