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What are the recommended first-line treatments for seborrhoeic dermatitis in adults?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

First-Line Treatments for Seborrhoeic Dermatitis in Adults

  • For Face and Body:
    • Offer ketoconazole 2% cream or another imidazole cream (such as clotrimazole or miconazole) 1.
    • Apply once or twice a day for up to 4 weeks 1.
    • An antifungal shampoo, such as ketoconazole 2%, can also be used as a body wash 1.
    • Once symptoms are controlled, ketoconazole cream can be used less frequently (for example, twice a week, once a week, or once every other week) to prevent recurrence 1.
    • For flares, a short course (up to 2 weeks) of a mild topical corticosteroid, such as hydrocortisone 1%, may be considered to help settle inflammation 1.
  • For Scalp:
    • Offer ketoconazole 2% shampoo, used twice a week for up to 4 weeks, followed by once every 1-2 weeks for maintenance 1.
    • The shampoo should be left on for 5 minutes before rinsing 1.
    • Scales can be removed by applying a keratolytic preparation (for example, salicylic acid) for several hours before shampooing 1.
    • Other medicated shampoos, such as zinc pyrithione, coal tar, or salicylic acid, can be used if ketoconazole is not appropriate or acceptable to the person 1.
    • For severe scalp inflammation, a short course of a topical corticosteroid scalp application (such as betamethasone valerate 0.1% or mometasone furoate 0.1%) can be considered once or twice daily to reduce itching and inflammation 1. Strong topical corticosteroid scalp applications are not suitable for application to the beard area; a mild topical corticosteroid (such as hydrocortisone 1%) should be used instead 1.

General Advice:

  • Seborrhoeic dermatitis in adults is a chronic condition, and long-term maintenance treatment may be needed 1.
  • Advise using a gentle, soap-free wash on affected areas and applying a light moisturiser after washing 1.
  • If wearing makeup, use non-comedogenic products that do not block pores 1.
  • Research suggests fruit consumption may help to reduce flares 1.
  • Stress may exacerbate seborrhoeic dermatitis and lead to flares 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.