You should consider referring a patient with suspected Dementia with Lewy Bodies (DLB) to a specialist dementia diagnostic service, such as a memory clinic or community old age psychiatry service, once reversible causes of cognitive decline have been investigated and dementia is still suspected NICE CKS,NICE NG97.
Reversible causes of cognitive decline include delirium, depression, sensory impairment (such as sight or hearing loss), or cognitive impairment from medicines associated with increased anticholinergic burden NICE CKS,NICE NG97.
Once referred, specialist investigations for suspected dementia may include structural imaging (MRI or CT scan) NICE CKS. If the diagnosis remains uncertain and DLB is suspected, the specialist may consider further tests such as 123I-FP-CIT SPECT or 123I-MIBG cardiac scintigraphy, particularly if knowing the dementia subtype would change management NICE CKS,NICE NG97.