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What are the indications for surgical intervention in patients diagnosed with cholesteatoma?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

Surgical intervention is the primary and only curative treatment for cholesteatoma 1. The extent of the cholesteatoma lesion determines the specific type of surgery required 1. For instance, mastoidectomy may be necessary if there is extensive disease 1.

Urgent surgical intervention is indicated in patients presenting with suspected cholesteatoma who also exhibit signs of serious or life-threatening complications 1. These include an associated facial nerve palsy, neurological symptoms or signs, or if the patient is systemically unwell, as these may suggest more extensive or advanced disease 1. Clinical features indicative of complications such as acute mastoiditis, intracranial abscess, or meningitis also necessitate urgent hospital admission or specialist ENT advice, often leading to surgical management 1. Delayed treatment in cases with facial nerve palsy is associated with a poor prognosis 1.

For all patients diagnosed with cholesteatoma, prompt referral to an Ear, Nose, and Throat (ENT) specialist is arranged for further assessment, confirmation of the diagnosis, and consideration of surgical intervention 1. High-resolution CT imaging of the temporal bone is often used to define the extent of the cholesteatoma, identify bony erosion, and assess for other complications, which guides surgical planning 1. Endoscopic management is also a recognized surgical approach for primary acquired cholesteatoma (Chiao et al., 2021).

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