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What acute treatment options are recommended for a patient experiencing a cluster headache attack in primary care?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

Offer oxygen and/or a subcutaneous or nasal triptan for the acute treatment of cluster headache in primary care 1.

Use 100% oxygen at a flow rate of at least 12 litres per minute with a non-rebreathing mask and a reservoir bag, and arrange provision of home and ambulatory oxygen 1.

Ensure the person is offered an adequate supply of triptans calculated according to their history of cluster bouts, based on the manufacturer's maximum daily dose 1.

Do not offer paracetamol, NSAIDs, opioids, ergots or oral triptans for the acute treatment of cluster headache 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.