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What follow-up protocols should I implement for patients treated for Conn's syndrome to monitor for complications or recurrence?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025
Follow-up protocols for patients treated for Conn's syndrome (primary hyperaldosteronism) should include:
- Regular monitoring of blood pressure to assess control and detect hypertension recurrence.
- Periodic measurement of serum electrolytes, especially potassium, to identify hypokalaemia or electrolyte imbalances.
- Assessment of renal function through estimated glomerular filtration rate (eGFR) or serum creatinine, as renal impairment can be a complication.
- Annual measurement of serum aldosterone and renin levels may be considered to monitor biochemical recurrence, although specific intervals should be guided by specialist advice.
- Cardiovascular risk assessment and management, given the increased risk associated with aldosterone excess.
- Imaging or specialist referral if clinical or biochemical signs suggest recurrence or complications.
- Coordination of care between primary and secondary care, with re-referral to endocrinology if symptoms recur or biochemical abnormalities persist.
These follow-up measures aim to detect recurrence of hyperaldosteronism, manage hypertension, prevent cardiovascular and renal complications, and ensure optimal long-term outcomes for patients treated for Conn's syndrome.
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