What topical treatments are recommended for corneal abrasions in primary care settings?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

For managing corneal abrasions in primary care, topical broad-spectrum antibiotics such as chloramphenicol are recommended to prevent bacterial superinfection, especially if there is a risk of infection due to contamination or foreign matter. Treatment is typically continued until 24 hours after the patient becomes symptom-free .

Topical anaesthetics should not be prescribed for ongoing pain relief as they can delay corneal healing and cause toxicity; their use is limited to a single dose to aid foreign body removal only .

Cycloplegics are not recommended as they do not improve healing or pain management and may worsen symptoms like glare .

Ocular lubricants (non-prescription lubricating eye drops or ointments) may be used to relieve symptoms, with drops preferred during the day and ointments at night due to potential blurring of vision .

Topical NSAIDs are not routinely recommended due to insufficient evidence of benefit and higher cost compared to oral analgesics .

Oral analgesia such as paracetamol is advised for symptom relief .

Educational content only. Always verify information and use clinical judgement.