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What initial investigations are recommended for a patient presenting with symptoms suggestive of FND?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

For a patient presenting with symptoms suggestive of functional neurological disorder (FND), initial investigations primarily focus on clinical assessment and exclusion of other neurological conditions rather than extensive routine testing. It is recommended to arrange referral to a neurology specialist for further assessment and confirmation of the diagnosis, as FND diagnosis is ideally made by a neurologist with expertise in neurological conditions 1.

Initial investigations may include structural and functional neuroimaging and neurophysiological testing when needed to differentiate FND from epilepsy and other neurological disorders, especially in cases of functional seizures 1. Videotelemetry electroencephalographic (EEG) recording can be useful to exclude epilepsy in patients with seizure-like events 1.

Routine blood tests or other investigations are not specifically recommended for FND diagnosis but may be considered to exclude other diagnoses based on clinical judgement 1.

In summary, the initial approach involves clinical evaluation, targeted investigations to exclude other neurological diseases, and early referral to neurology rather than broad initial testing in primary care 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.