What follow-up protocols should I implement for a patient who has undergone treatment for Cushing's syndrome to monitor for recurrence?

Arrange long-term follow-up in primary care to monitor for and treat any complications arising from Cushing's syndrome, such as diabetes, hypertension, osteoporosis, and increased cardiovascular risk ¹.

Follow-up should include regular assessment of biochemical markers to detect recurrence, although specific intervals are not explicitly detailed in the guidelines, it is recommended to individualise follow-up based on clinical judgment and local protocols ¹.

Monitor for signs and symptoms of cortisol excess or recurrence, including weight gain, hypertension, hyperglycemia, and Cushingoid features, during routine reviews ¹.

Consider offering vaccinations such as influenza, herpes zoster, and pneumococcal vaccines, as patients with Cushing's syndrome are at increased risk of infection, which may be relevant during follow-up ¹.