What are the potential side effects of common laxatives used in children, and how can I mitigate them?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Potential side effects of commonly used laxatives in children include:

  • Hard stools or stool withholding if laxatives are not used appropriately, which can lead to re-impaction or worsening constipation .
  • Abdominal pain and bloating, especially initially during disimpaction treatment .
  • Increased symptoms of soiling during disimpaction, which may be temporary .
  • Adverse effects specific to certain laxatives, such as electrolyte imbalance with electrolyte-containing macrogols, though these are generally well tolerated .

Strategies to mitigate these side effects include:

  • Gradually reducing the dose of laxatives over months once regular bowel habits are established to prevent re-impaction and maintain stool consistency .
  • Ensuring adherence to prescribed regimens and regular follow-up to monitor response and side effects .
  • Using the Bristol Stool Form Scale to assess stool consistency and adjust treatment accordingly .
  • Providing tailored dietary advice to ensure adequate fluid and fibre intake, which can help reduce gastrointestinal discomfort and improve stool consistency .
  • Starting treatment early to prevent long-term complications and avoid abrupt cessation of laxatives, which can cause relapse .

Educational content only. Always verify information and use clinical judgement.