What initial investigations should be conducted for a patient presenting with tremor to rule out secondary causes?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Initial investigations for a patient presenting with tremor to exclude secondary causes should include reviewing the patient's regular medication and checking thyroid function. Additionally, assessing alcohol consumption using a validated tool such as the Alcohol Use Disorders Identification Test (AUDIT) is recommended. These steps help identify reversible or secondary causes of tremor such as medication side effects, thyroid dysfunction, or alcohol-related tremor. Referral for neurological assessment is advised only if symptoms are disabling and first-line treatments are ineffective or not tolerated.

Educational content only. Always verify information and use clinical judgement.