The recommended first-line treatments for managing fever in children under 5 years are the use of antipyretic drugs such as paracetamol or ibuprofen, depending on parental preference, co-morbidities, or contraindications NICE CKS.
Paracetamol is normally given every 4–6 hours, with doses appropriate for age and weight, and the maximum daily dose should not be exceeded NICE CKS.
Ibuprofen is given every 8 hours, with doses tailored to age and weight, and should be used with caution if the child is dehydrated or hypovolaemic NICE CKS.
Antipyretics should be used when the child is uncomfortable or distressed, not routinely for all children with fever who are otherwise well NICE CKS.
They should be continued only as long as the child appears distressed, and if monotherapy is ineffective, switching or alternating agents may be considered NICE CKS.
Antipyretics should be stopped once the child is comfortable and not distressed NICE CKS.