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What monitoring protocols should I follow for a patient undergoing treatment for Graves' disease?
Answer
For patients undergoing treatment for Graves' disease, monitor thyroid function tests (TFTs) every 6 weeks until the TSH is within the reference range, then every 3 months until antithyroid drugs are stopped 1.
After stopping antithyroid drugs, measure TSH (with cascading) within 8 weeks, then every 3 months for a year, and annually thereafter 1.
During radioactive iodine treatment follow-up, measure TSH, FT4, and FT3 levels every 6 weeks for the first 6 months until TSH is within the reference range 1.
If hyperthyroidism persists after radioactive iodine treatment, consider antithyroid drugs until the 6-month appointment, with ongoing monitoring 1.
Post-thyroid surgery, if total thyroidectomy was performed, start levothyroxine and monitor TSH and FT4 at 2 and 6 months, then annually. For hemithyroidectomy, TSH may be measured annually 1.
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