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What are the recommended first-line treatments for managing Graves' disease in adults?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025
Offer radioactive iodine as first-line definitive treatment for adults with Graves' disease, unless antithyroid drugs are likely to achieve remission or are unsuitable 1.
Offer a choice of antithyroid drugs (a 12- to 18-month course) or radioactive iodine as first-line definitive treatment if antithyroid drugs are likely to achieve remission 1.
Offer antithyroid drugs (a 12- to 18-month course) as first-line definitive treatment for adults with Graves' disease if radioactive iodine and surgery are unsuitable 1.
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