What standardized tools or questionnaires are recommended for the screening and diagnosis of ASD in primary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Recommended standardized tools for screening and diagnosis of autism spectrum disorder (ASD) in primary care:

  • For adults without moderate or severe learning disability, the Autism-Spectrum Quotient 10-item questionnaire (AQ-10, British version) is recommended as a brief screening tool suitable for primary care, social care, and other non-specialist settings. It takes about 2 minutes to administer and requires no special expertise. A score of 6 or above suggests the need for referral for a specialist assessment for ASD ,.
  • For adults with moderate or severe learning disabilities, no standardized self-completion tools are recommended. Instead, a brief clinician-led assessment focusing on key behavioural indicators (such as difficulties in reciprocal social interaction, lack of responsiveness, rigid routines, and stereotypic behaviours) is advised to decide on referral ,.
  • For children and young people, no single standardized diagnostic tool is recommended to be used alone. Instead, autism-specific tools may be used to gather developmental history and assess social and communication skills as part of a comprehensive diagnostic assessment based on ICD-11 or DSM-5 criteria. The assessment should include detailed history, observation, and information from multiple sources (parents, carers, schools) ,.
  • Examples of comprehensive diagnostic tools used in specialist settings (not primary care) include the Autism Diagnostic Observation Schedule-Generic (ADOS-G) and the Autism Diagnostic Interview-Revised (ADI-R), but these are not recommended for routine primary care screening .

Summary: In primary care, the AQ-10 questionnaire is the recommended standardized screening tool for adults without learning disabilities. For children and adults with learning disabilities, clinical judgement supported by behavioural assessments and multi-source information is used to decide on referral for specialist diagnostic assessment ,,,.

Educational content only. Always verify information and use clinical judgement.