How should I manage a patient with recurrent bacterial vaginosis after completing standard treatment?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

When managing a patient with recurrent bacterial vaginosis (BV) after completing standard treatment, it is important to advise the woman that recurrence of symptoms is common .

  • Reconfirm the diagnosis: Perform a speculum examination and take swabs for pH, microscopy, and culture . Further examination and investigations may not be necessary if a previous episode of recognisably similar symptoms was diagnosed as BV, and symptoms/signs cleared after antibiotic treatment, and other conditions were absent .
  • Address contributing factors: Enquire about continued exposure to factors such as smoking, vaginal douching, and the use of antiseptics, bubble baths, or shampoos in the bath .
  • Review current contraception: For recurring BV in women with an intrauterine contraceptive device (IUD), consider removing the device and advising the use of an alternative form of contraception .
  • Treat the current episode: Prescribe a 7-day course of oral metronidazole 400 mg twice a day . If a single 2g dose of metronidazole or an intravaginal preparation was used previously, an alternative treatment like oral metronidazole 400 mg twice a day for 7 days should be prescribed .
  • Consider suppressive treatment or referral for frequent recurrence: If the diagnosis is confirmed and symptoms recur frequently despite adequate management in primary care, and symptoms are adversely affecting the woman, consider prescribing metronidazole vaginal gel as suppressive treatment (off-label use) if experienced in treating recurrent BV in primary care . Otherwise, discuss management with a gynaecologist or Genito-Urinary Medicine (GUM) specialist .
  • Partner treatment: Routine screening and treatment of male partners is not indicated . However, consider testing and treating the female partner in a same-sex relationship .
  • Probiotics: Current guidelines do not recommend probiotics for the treatment or prevention of BV, as systematic reviews have not provided sufficient evidence for or against their use .

Educational content only. Always verify information and use clinical judgement.

How should I manage a patient with recurrent bacterial vaginosis after