What are the indications for referring a patient with an adrenal incidentaloma to an endocrinologist?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

The provided UK guidelines do not explicitly detail indications for referring a patient with an adrenal incidentaloma directly to an endocrinologist based solely on the incidentaloma itself.

However, if adrenal insufficiency is suspected, which may be a consideration in patients with adrenal findings, an 8 am to 9 am serum cortisol test is recommended for people aged 1 year and over . For individuals aged 16 years and over, a serum cortisol level below 150 nmol/L indicates that adrenal insufficiency may be present, and referral to endocrinology is advised . For children and young people between 1 year and under 16 years, a serum cortisol level below 150 nmol/L also warrants recognition of possible adrenal insufficiency and referral to endocrinology .

Educational content only. Always verify information and use clinical judgement.